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Cassiopeia Build Guides, Runes, Items, and Abilities - Patch 14.16

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S14 Patch 14.16. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S14 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

Season 8 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

A can of Cass-whoopin

Build by partybus updated March 8, 2018
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia S8 Top/Mid build

Build by FireSkys22 updated January 29, 2018
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

% 100 w rate Twisted Treeline Cass

Build by TRevvorT updated December 13, 2017
8.9
32
Votes
5
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

S8 Cassiopeia Mid

Build by NTZL updated November 9, 2017
8.1
6
Votes
0
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia mid (New runes)

Build by Polsejensen updated November 11, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Nexz Cassiopeia Top and Mid in depth [Patch 7.23]

Build by Nexlovely updated November 20, 2017
Season 7 Guides
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

A complete and detailed guide to master the Snake (**WIP**)

Guide by Aminumbra updated August 1, 2017
  • In-depth
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia, The Sneaky Snakey SoloQ Monster

Guide by Collamis updated March 26, 2017
8.2
18
Votes
4
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Took me to Master with Cassiopeia in S6, OTP Guide

Guide by Corp Blue Cobra updated February 12, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Throwing A Mid Lane Hissy Fit

Guide by DeathWalker1 updated November 29, 2016
Season 7 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

[7.17]"There is No Antidote for Me"

Build by Lincoln878 updated August 26, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid [S7]

Build by WhichG updated July 16, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

INSANE ONE SHOT CASSIOPEIA BUILD

Build by Zambs updated July 13, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

CASSIOPEIA DEADLY BUILD

Build by HouYi updated July 8, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Build

Build by Danny1819 updated April 19, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

BROKEN BUILD

Build by Frog Cake updated March 29, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

The snake without an antidote

Build by nyle111 updated February 23, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

AP Carry Cassiopeia

Build by PiTeRoVs updated January 19, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

CASSIOPEIA HEALING GUIDE

Build by CassiopeiaONLY updated January 20, 2017
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia 1v9

Build by Korlo updated January 16, 2017
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Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 14.15. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.15: 17,695 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 52%

Win Rate 69% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 51%

Win Rate 15% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Resolve
LoL Path: Resolve
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 50%

Win Rate 13% Pickrate

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 84% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 5% Pickrate

Flash Ghost

Third Best

Cassiopeia's 3rd Best Summoner Spells 48%

Win Rate 4% Pickrate

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 74% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 58%

Win Rate 17% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 51%

Win Rate 56% Pickrate

  • 1
  • 2
  • 3
Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.15: 17,695 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 52%

Win Rate 70% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 52%

Win Rate 16% Pickrate

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 11% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Resolve
LoL Path: Resolve
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 89% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 48%

Win Rate 4% Pickrate

Flash Ghost

Third Best

Cassiopeia's 3rd Best Summoner Spells 50%

Win Rate 3% Pickrate

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 53%

Win Rate 68% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 56%

Win Rate 12% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 51%

Win Rate 46% Pickrate

  • 1
  • 2
  • 3
Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.15: 17,695 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 65% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 51%

Win Rate 15% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Inspiration
LoL Path: Inspiration
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 54%

Win Rate 10% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Resolve
LoL Path: Resolve
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 40% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 48%

Win Rate 24% Pickrate

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 54%

Win Rate 14% Pickrate

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 76% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 46%

Win Rate 11% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 49%

Win Rate 57% Pickrate

  • 1
  • 2
  • 3

Cassiopeia Counters

Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Cassiopeia MIDDLE in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Cassiopeia Skins

Cassiopeia's Abilities

Cassiopeia's Serpentine Grace
Serpentine Grace Cassiopeia's Passive Cassiopeia's Passive
Self
Cassiopeia's Passive
Cassiopeia's Passive
Cassiopeia gains 4 Movement Speed per level. Cassiopeia cannot purchase Boots items.
Q
Cassiopeia's Noxious Blast
Noxious Blast Cassiopeia's Q Ability
850
50 / 55 / 60 / 65 / 70
3.5
Cassiopeia blasts noxious gas, poisoning enemies and dealing 10.71 / 15.71 / 20.71 / 25.71 / 30.71 (+10% of ability power) magic damage over 3 seconds for a total of 75 / 110 / 145 / 180 / 215 (+70% of ability power). Hitting a champion grants Cassiopeia 30 / 35 / 40 / 45 / 50% decaying over 3 seconds.
W
Cassiopeia's Miasma
Miasma Cassiopeia's W Ability
700
70 / 75 / 80 / 85 / 90
24 / 22 / 20 / 18 / 16
Cassiopeia spews venom, leaving toxic clouds for 5 seconds. Enemies in the clouds take 20 / 25 / 30 / 35 / 40 (+15% of ability power) magic damage per second, are poisoned, grounded, and slowed by 40 / 50 / 60 / 70 / 80% for the same duration.
E
Cassiopeia's Twin Fang
Twin Fang Cassiopeia's E Ability
700
40
0.75
Cassiopeia launches deadly fangs, dealing 52-120 (+10% of ability power) magic damage (depending on level). If the enemy is poisoned, they take an additional 20 / 40 / 60 / 80 / 100 (+55% of ability power) magic damage and Cassiopeia restores 10 / 11.5 / 13 / 14.5 / 16% ability power as health.

If this kills the target, this ability's cooldown is refunded.
R
Cassiopeia's Petrifying Gaze
Petrifying Gaze Cassiopeia's Ultimate (R) Ability
850
100
120 / 100 / 80 / 80 / 80
Cassiopeia unleashes a petrifying gaze, dealing 150 / 250 / 350 (+50% of ability power) magic damage and stunning enemies facing her for 2 seconds. Enemies facing away are slowed by 40% decaying over the same duration instead.

Questions About Cassiopeia

Ask

Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

View (4) Answers

Which way is Katarina facing when she ults?

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

View (2) Answers

Question on Cassiopeia

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

View (2) Answers

Who should i choose?

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

View (3) Answers

Who is the most OP champion in the game?

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

I have no idea who I should buy; any suggestions?

View (8) Answers

Was Cassiopeia recently buffed?

Title.

View (1) Answers

cassiopeia at bot lane

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

View (4) Answers

Timing of a DoTs first "tick"

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

View (0) Answers

Lich bane Cass

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

View (2) Answers

Next AP Mid to learn and why?

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

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